Hospital-TTD-Mod: Technical Documentation
A multi-year Lexis simulation evaluating hospital tobacco dependence treatment (Document version number 1.0.0)
Front matter
Overview
The Hospital-TTD-Mod is a deterministic, multi-year Lexis simulation model designed to evaluate the health outcomes, health inequalities, and systemic cost-effectiveness of providing tobacco dependence treatment (TTD) to patients admitted to acute hospitals.
The model applies condition-specific potential impact fractions (PIFs) and decay curves for the excess morbidity risk of smoking after quitting to stratifications of Admitted Patient Care Hospital Episode Statistics (HES). By running distinct epidemiological and economic loops, the pipeline provides both short-term Trust-level budget impacts and long-term societal cost-utility outcomes.
Address for correspondence
Dr Duncan Gillespie
Sheffield Addictions Research Group
Sheffield Centre for Health and Related Research (SCHARR)
School of Medicine and Population Health (Division of Population Health)
The University of Sheffield
Regent Court, Regent Street, Sheffield, S1 4DA, UK
Email: duncan.gillespie@sheffield.ac.uk
Version information
This is a working version technical description and is subject to review and development. The document is up to date and relevant for Hospital-TTD-Mod version 3.0.0 for England and South Yorkshire.
License and citation
This report is licensed to The University of Sheffield under a Creative Commons CC-BY 4.0 license.
How to cite:
Gillespie, D, et al. (2026). Tobacco dependence treatment model (Hospital-TTD-Mod): full technical documentation. Documentation version number 1.0.0. The University of Sheffield.
Funding
Initial development of the Hospital-TTD-Mod originated from commissioned work by NHS England to review, consolidate, and improve upon previous modelling of the value for money from hospital tobacco dependence treatment services.
Model development was further supported by commissioned work from Yorkshire Cancer Research to evaluate the acute inpatient component of the QUIT Programme in South Yorkshire.